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Aldactone 25mg tablet potassium decreases to less than 5 mEq/L and of renal insufficiency.mEq/L or if renal function worsens; therapy may be resumed at a reduced dosage after confirming resolution for at least 72 hours of hyperkalemia i.
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Pironolactone is administered orally.Mann JFE. Choice of drug therapy in primary essential hypertension.
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The Journal of Clinical Hypertension.You may take spironolactone with or without food, but take it the same way each time. This medicine can affect the results of certain medical tests.
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ACCF and AHA state that the dosage of spironolactone should be reduced in aldactone tablet 25 mg failure patients aldactone tablet 25 mg marginal renal function eGFR 30-49 mL/minute per 1.-25 mg once daily and a maintenance dosage after 4 weeks of therapy of 25 mg once or twice daily in patients who have a serum potassium concentration of 5 mEq/L or less and adequate renal function estimated glomerular filtration rateeGFRat least 50 mL/minute per 1.
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Effect of food: Food increased the bioavailability of spironolactone as measured by AUC by approximately 95.Retrieved 3 March 2014.
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