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|Trade names||Sinequan, Quitaxon, Aponal, others |
|License data||US FDA: Doxepin|
|Pregnancy category||AU: C US: B (No risk in non-human studies)|
|Routes of administration||By mouth, topical, intravenous, intramuscular injection |
|Drug class||Tricyclic antidepressant (TCA)|
|ATC code||D04AX01 ( WHO ) N06AA12 ( WHO )|
|Legal status||AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only|
|Bioavailability||13–45% (mean 29%)  |
|Protein binding||76% |
|Metabolism||Hepatic (CYP2D6, CYP2C19)  |
|Metabolites||Nordoxepin, glucuronide conjugates |
|Elimination half-life||Doxepin: 8–24 hours (mean 17 hours)  Nordoxepin: 31 hours |
|Excretion||Urine: ~50%   Feces: minor |
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Multum's drug information doxepin fors sale not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this doxepin for sale as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.Sixty patients with chronic pain of the low back or cervical spine concomitant with clinical depression were studied in a 6-week, randomized, double-blind comparison of doxepin and placebo.
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Ricyclic antidepressants TCAs are a doxepin for sale of medications that are used primarily as antidepressants.41 It is the only TCA with a dibenzoxepin ring system to have been marketed. 67 Doxepin is a tertiary amine TCA, with its side chain-demethylated metabolite nordoxepin being a secondary amine.
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